Allogeneic Bone Marrow / Stem Cell Transplant
What is Bone Marrow Transplant (BMT)?
Bone marrow is the soft, fatty tissue inside bones that produces blood cells. A bone marrow transplant is a procedure where a damaged or destroyed bone marrow is replaced by healthy bone marrow stem cells.
Allogeneic Bone Marrow Transplant (BMT)
In this process, stem cells are taken from a donor. The donor could be a relative and must at least partly match your genes. The most effective way to match patients and donors is through human leukocyte antigen (HLA) matching. This is also called histocompatibility testing or tissue typing. HLAs are proteins covering most cells that dictate a person’s tissue type. A greater degree of HLA match between the recipient and donor improves overall transplant survival.
Indications of Allogenic BMT
- Non-malignant diseases
- Bone Marrow Failure States
- Immunodeficiency states
- Metabolic disorders
- Malignant diseases